BioResource 2014: Treating Tick-Borne Disease Using Integrative Therapies

BioResource hosted "Treating Tick-Borne Disease Using Integrative Therapies" on June 27-28, 2014 in Burlingame, CA.  Like their previous events, BioResource did not disappoint.  The two day event had some excellent speakers and shared a lot of information on some of the best products around - namely Beyond Balance, Pekana, and Syntrion.  

Disclaimer: Nothing in this text is intended to serve as medical advice. All medical decisions should be made only with the guidance of your own personal medical authority. This information was taken as notes during the conference and may not represent the exact statements of the speakers. Errors and/or omissions may be present. If you have any corrections to the content listed below, please Contact Me.

Note: As this information may be updated as any errors are found, I kindly request that you link to this single source of information rather than copying the content below. If any updates or corrections are made, this will help to ensure that anyone reading this is getting the most current and accurate information. 

These notes are brief highlights from the event as much of the discussion was geared more towards practitioners and how to use the specific products.  Nonetheless, there were some great topics discussed, and I'll share some of them here.  The key speakers included Kristine Gedroic MD, Raj Patel MD, Susan McCamish CTN, and Joseph Burrascano MD.  Talk about some heavy hitters!

Dr. Kristine Gedroic shared some of the following points: 

• In order to regain wellness, we need to detoxify, control, infections, and restore and repair membranes.
• Symptoms are the result of the sink overflowing. We have to slow down the faucet or open the drain. German Biological Medicine remedies are very effective in opening the drains. Without drainage, you can only control the faucet.
• Heel was founded by Dr. Reckeweg. 
• The extracellular matrix is involved in transport, storage, and intercellular communication. The cells of the body are like holes in a sponge; the matrix is the sponge. German Biological Medicine provides tools to help us ring out the sponge.
• There are six phases in Homotoxicology. It is generally easier to help patients in the first three phases than the last three; the last three have lower vital force and can be more difficult to treat. The left three phases are matrix where the right three are cellular; including nucleus and DNA.
• Pekana has a number of regulating and drainage remedies. 
• Homotoxicology marries homeopathic with allopathic. 
• Provoking remedies dislodge toxins in specific local tissues. 
• Regenerating remedies repair and supplement Qi; increase vital force.
• Immunometabolic remedies reset the computer and reboot the immune system. They teach the terrain not to host Candida, for example.
• MUCAN is often a useful remedy for a number of infections and for microbial debris.
• MUNDIPUR drains through the biliary tree. Also supports liver and gallbladder. It is a good place to start.  Regenerating remedy.  It is very safe and facilitates bowel movements.  It may assist with draining of rheumatic toxins.
• OPSONAT is one of her favorite remedies for mucosally-derived toxins. It can help with inflammation and many of the "itis" conditions.  It support clearance of infections and toxins in the bowel, sinuses, and joint tissue.
• TOXEX is a matrix drainer.  Assists the body with metals and xenobiotics.
• VISCUM can be helpful in some cases of neuropathy. It may support those with tics, Tourette's.  apo-STOM with VISCUM may support asthma.  Helps in some cases of MS.
• apo-PULM And BRONCHI-PERTU are restorative for the lungs; apo-TUSS is regulating.  apo-PULM is more of a wet cough; BRONCHI-PERTU for an asthmatic cough.  
• coro-CALM may help some with heart palpitations.  CARDONORMA may be better if there might be infection in the heart such as Bartonella or Borrelia.  
• apo-ENTERIT may help with a crampy bowel. 
• apo-STOM helps to drain the stomach and dial down a protocol; settles down.
• JUVECAL can be restorative in early cases of leaky gut.
• For constipation, DEFAETON and OKOUBAKA may be helpful.  DEFAETON is for dry constipation and can be paired with MUNDIPUR.
• GLUCORECT supports metabolic syndrome.  May help with Hemoglobin A1c elevation.
• SPECI-CHOL is provoking to dislodge toxins.
• For the adrenals, SUPREN is for the adaptive phase and NEU-regen is for the more depleted adrenal presentation.  Best in the morning and 12pm-2pm but not in the evening if sleep is an issue.
• INFLAMYAR supports reducing inflammation and is often great for kids.  The drops may be best for myalgia or inflammation associated with infection.  The cream is a good option for local injury or inflammation.  ZELLULISAN supports against tendonitis.
• DEMYC may assist with topical fungal infections, ring worm, and similar conditions.
• KELAN may assist with scars.
• apo-INFEKT is the little sister to MUCAN.
• RICURA may help those with sinusitis. 
• SEPTONSIL has been helpful in many children to avoid surgery for removal of the adenoids.
• PROALLER supports those with an environmental or food allergen picture.
• KLIFEM supports those in perimenopause.
• HABIFAC may benefit those with miasms.  A child with alopecia universalis regrew hair.
• FERRADONA helps in those with iron deficiency.  Can help standalone or in combination with iron supplements when not tolerant of them.  
• PEVENT supports healthy blood lipids.  May assist those with high lipids and metabolic syndrome.  Some find it helps to reduce body fat.
• OSS-REGEN supports bones.  Can help with osteoporosis.  Supports bone marrow.  May support autoimmune regulation.
• apo-HEPAT supports Phase 1 Liver detoxification. SyDetox supports Phase 2.  They can be used together.
• DALEKTRO N is like homeopathic electrolytes.
• PSY-STABIL supports those with anxiety. 
• CANGUST may support against H. Pylori.
• CLAUPAREST can be helpful for those with Raynaud's.
• HELMIN is a stronger remedy to help support the body against parasites.
• AKUTUR may be useful in cases of bed wetting.
• OTIDOLO may help with otitis externa. 
• RADINEX helps support against radiation. Dosages usually go down over time.
• CITRIPLUS, FORMILUS, and LACTIPLUS help the mitochondria after a bad virus. Also useful on those with exercise intolerance.
• Practitioners often pair a regulating remedy with a provoking remedy.  
• SanPharma are often better tolerated. Don't have to worry as much about reactions as they have removed the antigens and include only metabolic products.
• Notatum is the master remedy for inflammation and bacterial infection. Suppositories are stronger. 
• Quentans may be helpful with Coxsackie. 
• Roqueforti can be used with notatum (inflammation) or quentans (infection).
• Firmus is often used at the end of treatment.
• Candida (a remedy) supports regulation of the intestinal terrain.
• Syntion SyAllgen may help with immune system hyperreactivity and balance of Th1/Th2.
• SyImmune accelerates adaptive immune responses and may help with colds.
• SyImmune nasal spray may help with MARCoNS. SyFungin nasal spray for fungal issues.
• SyCircue is great for reactive patients. May help with Raynaud's and circulatory issues. Dark circles and low perfusion states. 
• Should all be used on an empty stomach.
• A hot liver is when people are living too richly with alcohol, fatty foods, cigarettes, etc. In these cases, SyDetox may be better than apo-HEPAT.
• Drainers should be succussed about 10 times before use. Pekana remedies can be mixed together.
• If one is alcohol sensitive, you can setup your dose hours before to allow it to off-gas. Can boil a kettle, let it cool slightly, and pour warm water over the remedies and then let it come to room temperature. This will flash off the alcohol. 
• Eczema is often a sign that additional detoxification is needed and the body is detoxifying through the skin. 
• DEMYC can be helpful for nail fungus.
• When there is environmental mold exposure, this often leads to fungal growth within the body.
• H. Pylori is often a deeper pathogen that comes up later in treatment.

 Susan McCamish shared the following:

• One of the benefits of herbs is that they can help with various forms of Borrelia. They have broader spectrum coverage for the spirochete, L-Form, and cyst forms. 
• Antibiotics in general weaken overall constitution while herbs support the constitution at the same time that they perform they primary role in the protocol.
• Herbs can reach some of the intracellular infections.
• Toxins are a source of inflammation. 
• Dr. Gedroic mentioned that the Lomatium from Eclectic Institute is one that she really likes. 
• Fungal overgrowth is common in children on the spectrum.
• One doctor at the event mentioned that she finds the Beyond Balance Parazomin blend to work better in her clients than Vermox.
• Dr. Gedroic mentioned that in general the RX antivirals don't work very well in her patients and that the herbals often shine here.

Dr. Burrascano shared some of the latest in the Lyme realm: 

• Bartonella is one of the most difficult to treat.
• Lyme testing is done with the B31 strain which was a lab strain and has never been in a human. It was derived from a tick and had never tasted human blood. This is part of why lab testing is so inaccurate.
• There are 263 references in Dr. Horowitz book that support the persistence of infection.
• Borrelia is thousands of times less sensitive to antibiotics than syphilis.
• Ticks cannot survive drying out; moisture is their friend.
• If there were no deer, ticks would move to other large animals. Reducing the deer population does not work as a way to reduce ticks. Birds also carry ticks and the flyways for birds overlap endemic areas for Lyme.
• Borrelia garinii has been found in North America. Borrelia andersonii and Borrelia americana have been found in Florida. Borrelia lonestari has been found in the Southeast.
• There is a significant Borrelia problem in Africa and it can be transmitted within minutes of a tick attachment.
• It takes a temperature of 17 below zero to kill a tick. 
• Borrelia has the most complex genetic makeup of any known bacteria.
• Ebola, HIV, and Borrelia have all been tested in the Space Lab.
• Symptoms change with Borrelia every few days and more obviously every 4 weeks. This is due to epitope switching. The body sees the infection is gone and a new infection is present. IgM keeps coming up again.
• Borrelia secretes blebs which can lead to false positive ANA's. The DNA in blebs can be shared between Borrelia via gene exchange.
• Transfection is when segments of Borrelia incorporate into our own human DNA. The human then makes Borrelia proteins. Part of the problem becomes our own body making more Borrelia proteins.
• Borrelia garinii is more likely to produce a larger EM rash. A skin presentation known as acrodermatitis chronica atrophicans (ACA) is associated with Borrelia garinii and occasionally with Borrelia afzelii.
• CSF testing for Borrelia is 91% inaccurate according to Dr. Patricia Coyle of SUNY Stony Brook. 
• Borrelia miyamotoi may produce GI symptoms. It seems to have a 2.5 week cycle instead of a 4-5 weeks cycle. 
• Band 18 and 100 on a Western Blot are often the result of a European Borrelia strain.
• American blood tests are poor at picking up European strains.
• Spiral Borrelia can segment and result in 20 or more new spirochetes.
• 5-10% of ticks have Borrelia in the mouth parts which allows for rapid transmission in some cases. 24-48 hour timeframe for transmission was based on rabbits and is not reality.
• Relapsing fever may be transmitted in as little as one minute. Other infections can be transmitted in minutes with regurgitation transmission. Tick feces can get rubbed into a wound and cause infection.
• Borrelia BR91 strain is found in mosquitoes. It could be that a mosquito is squashed and germs are rubbed into a wound. This has not been proven but is a theoretical possibility. Sand flies and horse flies may be sources of transmission of infection.
• Some are exploring Borrelia protease possibly for diagnostics, vaccinations, or treatment with protease inhibitors. 
• Borrelia inhibits B cells, T cells, and NK cell maturation. CD56 NK cells mature to CD57. Borrelia inhibits the maturation to CD57. 
• We have both innate and adaptive immunity. Innate is related to B cells which create IgM. Adaptive is associated with T cells. T cells signal the shutdown of B cells which then shifts the immune response from IgM to IgG. Borrelia stops the shutdown of B cells which means that we keep creating IgM that is ineffective at killing Borrelia. This continued response of the innate immune system results in cytokine storms.
• Steroids make Lyme worse and prevent the development of IgG antibodies. Allows the continued production of ineffective IgM. Steroids increase the number of spirochetes in tissues. 
• Borrelia can affect the gut. In one study, Borrelia was found in 10 of 10 studied. Coinfections also impact the gut. 37% in a separate study had a single pathogen; 24% had 2; and 8% had 3. Some of the pathogens identified included Bartonella, H. Pylori, Mycoplasma fermentans, and Borrelia.
• In studies by Eva Sapi, Doxycycline reduced spirochetes but increases the round body forms. Flagyl notably reduced both spirochetes and round body forms. Tigecycline and Tinidazole reduced both forms notably as well. With biofilms, only Tinidazole appears to reduce organisms. 
• Is Lyme an ongoing infection or autoimmunity? There is an overlap. Plaquenil or IVIG can be helpful. 
• Band 31 is cross reactive with neural tissue as are 34 and 41. There may be a relationship between these bands and positive anti neural antibodies.
• When people have neuropathy, a skin biopsy may show that the nerves are wiped out. This can be helped with IVIG. 
• A team is working on myelin staining of the nerves in the skin which is a more sensitive way to evaluate. It is accurate enough to get coverage for IVIG which can run $15,000 per week for 6 months to 1 year. This technology should be available as a skin punch biopsy by the end of the year.
• When nerves are involved, test for mycotoxins and heavy metals. IVIG may help in 80% of cases. Other options for nerve healing include R Alpha Lipoic Acid, Pharmanex Cordymax, high dose CoQ10, NT Factor, and MB12. Cordymax has helped in patients with Parkinson's.
• IVIG stops cytokine storms without suppressing the immune system. 
• Ticks are nature's dirty needle.
• Nematodes (worms) have been found in ticks. Filaria were found by Dr. Sapi from the Onchocercidae family; specifically Acanthocheilonema. 22% of nymphs and 30% of adults had these worms.
• There was some discussion with the attendees around Babesia duncani being one potential cause for anxiety and it seemed that some have observed this connection.
• Bartonella lives mainly in the RBCs. There are at least 30 species. They are treatment resistant. No one regimen works. They have been found in gastric biopsy and in a biopsy of striae commonly seen with Bartonella.
• They can be intravascular and intracellular. They may be in or on the surface of the RBCs. 
• Advanced Labs prepares the blood with hyaluronic acid before the culture to release bacteria that are adherent to the red blood cells.
• Some veterinarians recognize that Bartonella may not be curable in animals.
• Some of the medications are inhibitory but may not be "cidal" (killing). 
• For Bartonella, Levaquin is by far the best (though does have side effects that can be long-term). 
• Combinations for intravascular and intracellular properties are needed.
• Fluoroquinolones work in both spaces but there have been resistant strains documented.
• Macrolides only work intracellularly. Ketek may be the best. It was his favorite Lyme drug but can be toxic and may not be easy to get anymore. Tetracyclines are a poor choice. Gentamycin is effective but not in the CSF and can also be toxic. No amount of Doxycycline will work. Bartonella develop resistance to antibiotics very quickly. Resistance may occur quickly to Zithromax when used alone.
• Some combinations for Bartonella may include Augmentin plus Levaquin, Ceftriaxone plus Ketek or Biaxin, Doxycycline plus Ketek or Biaxin, Rifampin plus Ketek or Biaxin. 
• Cell wall drug + fluoroquinolone or ribosomal drug + Rifampin would be a triple drug regimen.
• In some cases, Gentamicin may be added but is not used alone.
• For Bartonella, 3-4 months of antibiotic treatment is a minimum.
• Some effects of Bartonella may be counteracted with L-Arginine. Some Bartonella lead to elevated VEGF which can be measured serially to track treatment progress.
• Bartonella may be immunosuppressive like Tularemia. Acai has been helpful. 
• Intranasal IL-12 and intranasal synthetic TLR4 may be helpful therapeutics.
• Overstimulation of the immune system can result in tissue injury. It is more about modulation than stimulation. 
• Transfer factors can be very helpful as can stimulation of the cholingeric anti-inflammatory pathway with Galantamine. Galantamine upregulates IFN-a and downregulates IL-6. Anisodamine and Puerarin may also be helpful. Huperzine A and Curcumin may also help with the stimulation of the anti-inflammatory pathway. 
• Transfer Factors are good modulators and help to control overreactions.
• Mepron is poorly absorbed. Need a blood level in the low 20s to have much effect. In some cases, had to use much higher doses to get those levels. Babesia also develops drug resistance. Coartem, Sulfa drugs, Zithromax, or Flagyl may need to be added. Blood level test can be done through Quest.
• Some new research is being done using gamma globulin into the spinal canal for people with ALS via a port. It has been a small sample of 7-9 patients, but all have stabilized.
• There is Lyme-induced ALS which may be autoimmune and there is genetic ALS where there is early death of motor neurons. These are not the same condition.
• IM Bicillin can be a very good option for Lyme treatment.
• Cytokine mediated inflammation is a dilemma. If you start with lower doses of drugs, you may have a higher incidence of drug resistance. You have to treat aggressively and then get a Herx. If the herx is not tolerable, then stopping the treatment entirely to allow recovery from the herx is a better option than lower doses. 
• Labcorp has several offices that do the CD57. In his clinical days, the results were very reliable. That may not be the case with several testing sites if the results are not consistent. The IGeneX CD57 is likely to be more consistent. The number is not as important as the percentage. 
• Stonybrook does a Western Blot that is covered by insurance. They do report CDC bands only, but you can ask for reporting of all bands.
• Even the advanced Bartonella testing at Galaxy Labs may only detect 20-30% of Bartonella infections.

Dr. Kristine Gedroic delivered two more excellent talks. Here were some of the highlights:

• She treats biofilms universally in patients with chronic infections.
• When we are not well, that means we are blocked. 
• We are not muscling the system towards wellness, but removing blocks to allow it to heal naturally. Release the blocks.
• Some if the Syntrion remedies have been very helpful in her practice. SyAllgen for allergic reactions; SyCircue for inflammation; SyDerm for skin issues; SyDetox for liver detoxification; SyFungin for fungal infections; SyGest for dysbiosis, SyImmune for immune reactivity; SyInfect for infection; SyReflux for GERD; SyRegule for fungal dysbiosis; SyResp for MALT dysbiosis.
• When patients have autoimmune issues, go back to the gut protocols. Much happens in the GALT.
• SanPharma remedies have also been very helpful. Notatum for infection and inflammation; Quentans for infection and viral issues such as Herpes, Shingles, and Coxsackie; Roqueforti for gut dysbiosis; Candida for fungal dysbiosis and immune dysregulation and autoimmunity; Firmus for membrane inflammation, creeky joint pain (can result in a powerful download), Mycobactin S for immune support; Subtilis as an immune adaptogen.
• Uses a number of the Beyond Balance Herbal remedies. 
• Uses less and less antibiotics but may still use targeted, short term IV therapy at the right time.
• Some patients that are coming off antibiotics can often go to Beyond Balance BB-2; whereas most people need to start with BB-1 if they have not already been treated for Lyme.
• One of her favorite remedies is BAR-1. Seems to support patients with epierythrocytic bacteria as well as being helpful for Mycoplasma and Chlamydia. BAR-2 may also be helpful for Mycoplasma and Chlamydia.
• Desbio Ver has been a helpful homeopathic for nematodes and DesBio Amoeba for smaller parasites.
• Sees massive improvements with parasite treatment - as much as 40% in 6 weeks. 
• Beyond Balance IMN-V may be used for HHV-6, Herpes, EBV, CMV, and Parvo viruses. 
• When someone has laryngitis or hoarsness every month, consider Coxsackie. 
• When treating biofilms, this can release heavy metals, and TOX-EASE II has been helpful.
• OGN-DI may support those with spleen and stomach deficiency. 
• Beyond Balance BFM blend has been remarkable for her practice. 
• Biofilm is the medium by which chronic infection exists in the body.
• Guggul modulates cytokines and addresses biofilms.
• EMF and geopathic stress are major considerations.
• CYFLACALM seems to work in more arthritic patients where CYFLACALM II seems to help with burning, parasthesias, and in supporting the vascular and nervous system.
• Frontal headaches are often Babesia; bitemporal often Bartonella; back of head often Lyme.
• In thinking about mitochondrial support, stimulant medications often lead to more problems. May need to explore viruses.
• Parasthesias can be Lyme, Bartonella, or viruses.
• Pustular eruptions on the scalp may be associated with parasites.
• Ringing in the ears may be related to Babesia or viruses.
• Sinus pressure may be Babesia; cycling sore throats and swollen glands Bartonella.
• Babesia may lead to shortness of breath, air hunger, panic, difficulty with falling asleep, sleep cycle disturbances.
• Bartonella may present with reflux, abdominal pain, striae, wrist/hand/finger pain, morning foot pain, and anxiety.
• Chronic cough is often related to Mycoplasma.
• Nausea and vomiting every month or so may be related to Babesia.
• Bartonella impacts the smaller joints; Borrelia the larger.
• Muscular pain and weakness may be viruses or Ehrlichia.
• Twitching can be electrolyte or mineral imbalance and may be helped with Viscum.
• For testing:
• Uses IGeneX IFA/WB/PCR, Babesia FISH, and Bartonella FISH.
• LabCorp coinfection testing is often helpful.
• Fry Labs stained blood film and advanced stain for Protomyxzoa is helpful; including their testing for biofilm.
• Advanced Labs has a Borrelia culture which can be helpful.
• MDL is a good option for PCR for viruses and some bacteria.
• She has TBD panels through LabCorp, Question and Bioreference Labs; including coinfections.
• Doctor's Data for urine toxic metals. LabCorp Heavy Metals 2 panel often shows some metals on high normal side.
• Vitamin Diagnostics for KPU. 
• MTHFR
• Vitamin D and calcitriol - if calcitriol is high, this could be an indicator of intracellular infection.
• Successful treatment involves detoxification, controlling infections, and restoring and repairing membranes.
• Have to consider the patient's constitution in determining how to approach treatment. Are they made of straw or brick? Traditional Chinese Medicine and German Biological Medicine take these into consideration.
• Environmental or occupational toxin exposures are always there in the sickest patients. 
• Herbs offer nutrition to the body in addition to their killing or "cidal" properties.
• For nutrition, uses things such as BodyBio or NurtraSal PhosCol, BodyBio Balance Oil, Flora or BodyBio Sunflower Oil, BodyBio Kirunal High EPA oil, Evening Primrose Oil. 
• For probiotics, Therbiotic, Saccharomyces Boulardii, Syntol, AMD, and VSL#3 are good options.
• If a patient is really depleted, may need to add electrolytes, trace minerals, cells salts, protein, adrenals, and GI.
• For electrolytes, ELyte, Wright Salt, DALEKTRO-N, or Selectrolytes. BodyBio Liquid Minerals for trace minerals; Schuessler Cell Salts.
• For protein, consider egg white, hemp, white fish, or pea protein.
• For adrenal support, Vital Nutrients Adrenal Support, NEU-REGEN, SUPREN, or Drenamin.
• For GI support, GI Repair Nutrients, Roqueforti, SyGest, SyRegule, or butyrate.
• It is virtually impossible to get vegetarians better.
• For gut dysbiosis, a Paleo diet, probiotics, GI Repair Nutrients, Energetix Core Pau D Arco, Energetix Core Berberine, and OPSONAT can be helpful. 
• For the nervous system. PSY-STABIL, VISCUM (when tremors are present), SyDetox, SyCircue, DALEKTRO-N, ELyte, Wright Salt, SR3 Balance Oil, PhosChol. apo-STOM, SyDetox, and VISCUM can be a nice approach.
• Omega 6 to Omega 3 ratio should be 4:1. You can have too much Omega 3. Viobin Prometol can be a good option. 
• For herxheimer reactions, matrix drainage, Parsley, Burbur, and Pinella. Alkalanizing with Alka Seltzer Gold, Alkabase, Magnesium Carbonate, Potassium Bicarb, lemon water. LDN can also help with herxheimer responses. 
• In her practice, there has been 80% less herxing since incorporating drainage remedies.
• Protomyxzoa is found in mosquitoes. There are at least 5 strains in the US. It is hard to distinguish between Protomyxzoa and Babesia. 
• Biofilms are made of lipids, protein, nucleic acid, and polysaccharides. 75-95% is extracellular polymeric substance (EPS) and 5-25% is bacteria. 
• 65% of infections involve biofilm according to the CDC.
• When in a biofilm, organisms are 1000 times more resistant to antibiotics.
• Organisms and biofilms communicate through quorum sensing and can sense epinepherine/stress.
• There may be a correlation between MTHFR and biofilm formation.
• Low zinc is often associated with heavy metal toxicity.
• Kids with speech delay almost all have biofilms.
• When people have tics, this is suspicious for Bartonella or a combination of Borrelia and Bartonella or possibly mold.
• Talked about a patient that was intolerant to all treatment. Gave her CYFLACALM-II with TOX-EASE GL and IMN-R for a few weeks and then the patient was able to tolerate other treatments.
• Low ferritin can be a sign of Babesia.
• apo-STOM, PSY-STABIL, VISCUM, and SyDetox can be a good calming combination. 
• 100-120 days of treatment may be required to clear the spleen of Babesia.
• Drainers should always be taken on an empty stomach.
• She uses BFM for biofilms with drainers then does the antimicrobials 15 minutes later.
• Ehrlichia may be treated with Byron White A-BIO or A-RMSF or DesBio RMSF. 
• Has found BAR-1 to be helpful for Rickettsia. 
• In standard testing panel, tests for West Nile, Coxsackie, HSV-1, HSV-2, HHV-6, and Parvo viruses.
• With the Pekana drainage kit, some use 1/2 teaspoon of each of the 3 products twice daily. 
• Hives may be an indicator of a biofilm. Lyme can also cause a secondary rash that looks like hives according to Dr. Burrascano. Suggested that a biopsy will often show spirochetes. Look for plasma cells. 
• When a child has PANS, TOX-EASE GL or CLA-K Detox can be helpful drainers. SyDetox + PSY-STABIL + VISCUM + apo-STOM can also be helpful. May use antibiotics first and then introduce herbs later.
• She has seen enormous jumps in CD57 when implementing Beyond Balance BFM (biofilm) and parasite treatments. 
• When CD57 goes down and EOS goes up, think parasites. Then after months of treatment for parasites, CD57 will often go up. 
• Fibromyalgia is an accumulation of toxins in specific focal locations in the body.
• Mycoplasma and Chlamydia can both be airborne. 
• Dr. Burrascano shared that in one small study of 4 gallbladders, they all had Borrelia. Borrelia do not like oxygen and the gallbladder is very low in oxygen. People often feel better when they have their gallbladders removed.
• MUNDIPUR, TOXEX, or OPSONAT can be helpful for supporting the gallbladder. 
• For liver and gallbladder flushes, it is important that you have a person with a stronger constitution.
• Too much Vitamin D can make things worse for Lyme.
• In some patients were even BFM-P (pediatric dosing of biofilm blend) is too much, she may use Serrapeptase.  

Dr. Raj Patel and Susan McCamish delivered a "duet" presentation and shared the following: 

• Seizures can often be related to Bartonella.
• Melatonin pre and post endotoxin challenge attenuated liver toxicity. Melatonin is an antioxidant.
• 18-45% of patients do not experience a Herxheimer reaction.
• Looking at HLA status is important. If someone has a Lyme-susceptible type, the focus is on treating the Lyme. The body has a difficult time binding to and excreting antigens which results in recirculation and triggers more inflammation and higher C4a.
• 22% are Lyme susceptible in the general population. In his patients in a sample of 64 people, 86% were Lyme or multisusceptible. 
• Lyme is a bacteria and you would expect a neutrophil response.
• If CYFLACALM is too strong, it can be taken with food. Ginger can be antiparasitic and that may be a reason why some find the formula strong.
• Too many pro-inflammatory cytokines can suppress the immune system, lead to pain, decrease hormones, disturb sleep, decrease brain function, increase fatigue, cause muscle wasting, and lead to depression.
• Most with Lyme need to be gluten free, casein free, and sugar free. 
• Carbohydrate intolerance leads to increase in bacteria and yeast.
• We need to get 8-10 hours of sleep per night. Melatonin, theanine (anxiety), Phos Serine (for hyperadrenal Type A), Benadryl, valerian, and kava kava may be helpful.
• Almost all Lyme patients that are not recovering in his practice were living in a moldy environment. A HERSMII-2 score > 11 is a clue to mold.
• Lyme generally takes C4a to around 10,000. In mold patients, it can be significantly higher. 10% of his patients have normal C4a.
• Can do a glutathione and sauna challenge before the Realtime Labs urinary mycotoxin test collection. Often uses 1/2-1 teaspoon of Researched Nutritionals Tri-Fortify.
• For the liver, milk thistle, bupleurum, Liver Life, glutathione, apo-HEPAT, MUNDIPUR, Cholestyramine, supervised liver/gallbladder flushes, and coffee enemas can be helpful.
• Pure Encapsulations Liver GI Detox supports both Phase 1 and Phase 2. 
• Caffeine intolerance may be a clue to phase 1 liver detoxification issues.
• Takesumi Supreme may be a broader binder than Cholestyramine. In some cases, both are used concurrently.
• Immune insufficiency can be supported with immune globulins, transfer factors, AHCC, probiotics, & colostrum. Inflammation may be an issue when C4a is elevated and can be supported by Cholestyramine, low dose antivirals, INFLAMYAR, MUNDIPUR, A-INFLAM, Skullcap, CYFLACALM, or NSAIDS.
• Viral support may include low dose Valcyte, Valtrex, Famvir, IMN-V, IMN-V-II, IRM, and Viralox. 
• Kidneys may be an issue when creatinine is elevated or back pain is present. Support includes K-Drain, RENELIX, Dandelion, and Parsley.
• Adrenals and thyroid may be an issue when symptoms of POTS present or there is an inability to tolerate stress. 24 hour saliva cortisol is often used. T3, T4, iodine, Adrenal Support, and rest may be helpful.
• Lymphatics and Extracellular Matrix are almost univerally in need of support. Need adequate water, avoid caffeine, exercise (at least walking), homeopathic drainage remedies, skin brushing, and lymphatic massage.
• For parasites, testing can be done through Genova, Doctor's Data, DiagnosTechs, Parawellness Research. Even with these options, only get a 10-15% positive rate when actual incidence may be higher.
• For viruses, look to see if SAM is low or adenosine is elevated. Conversion of methionine to SAMe is compromised with viral load.
• Prioritize: Parasites, Babesia and/or Bartonella, Ehrlichia, Borrelia, stealth pathogens (inflammation), and viruses (inflammation).
• For parasites, MC-PZ can be very helpful for protozoans including for Blastocystis. For helminths/nematodes, Biltricide, Albenza, and Ivermectin may be considered. Other options include PARAZOMIN, Aromatab, Paratrex, and Diatomaceous earth.
• For Babesia, Coartem + Artemisinin may be considered for 3 days every month. BAB-1, BAB-2, CryptoPlus, A-BAB, and Enula are other options.
• For Bartonella, antibiotics, BAR-1, BAR-2, A-BART, and Houttuynia may be helpful.
• For Ehrlichia, antibiotics, BB-1, BB-2, or A-L Complex may be used.
• For Chlamydia, BAR-2 and A-CPN may be used.
• For Mycoplasma, A-MYCO or ENL-MC may be helpful.
• Reducing viral load opens up methylation. 
• GcMAF can be an excellent tool as a last step in treatment. Want a 0.6 or lower target for nagalase.
• Pau D' Arco and Cat's Claw may support against H. Pylori.
• Dr. Shoemaker protocol doesn't include consideration of fungal colonization in the nasal passages.
• Low dose vitamin C may be helpful but 50 grams or more is a pro-oxidant.
• For treatment of asymptomatic partners, Dr. Burrascano suggested treating the average male for 4 months and average female for 6 months; often with Amoxicillin and Probenecid.

Dan Kenner LAc spoke on essential oils: 

• Wrote the Whole Body Workbook for Cancer.
• Pharma grade oils are prescription items in France.
• You match the characteristics of the oils/herbs to the 5 elements and the person's type.
• Essential oils dissolve biofilms; most of them do this.
• Can dissolve cystic membrane walls and penetrate blood-brain barrier as well as the interior of cells.
• He likes oil of savory - antiviral, antifungal, antiprotozoal.
• Oil of savory and oil of thyme might be used for 2 weeks.
• Oil of thyme is one of the best for worms and is antifungal.
• 92% of bronchitis is viral. 
• Can use gelatin capsules with 2-6 drops of essential oil and either rice bran or olive oil.
• Oil of clove or oil of cinnamon (antifungal). Cinnamon can rev people up in some cases.
• A European product called Tic-Tox was an antimicrobial blend for Lyme from Bernard Christophe in Strasbourg, France.
• Mentioned a device called the Biowave Goldstream.