In my experience, very similar to testing for Lyme disease, there is no one perfect test for exploring mold and mycotoxin-associated illness.  As a result, it is often important to explore the potential for mycotoxins through several different "lenses".

At the guidance of my doctors over many years, I personally have found urine mycotoxin testing to be very helpful in my own journey, and yet, I acknowledge that these are also not perfect tests.  Some will suggest that mycotoxins in the urine are normal, healthy excretion, and that may be true.  At the same time, if someone is chronically ill and has high levels of mycotoxins coming out in the urine, my doctors have always asked why there are high levels being excreted and may interpret a high level to mean that there are high levels of mycotoxins either environmentally or resulting from internal colonization. The other explanation might be that mycotoxins were not previously being detoxified efficiently and that as detoxification is supported, higher levels could be a positive sign that one is moving in the right direction; if their clinical symptoms match up and they are improving.

That said, someone can have mold and mycotoxin-associated illness and not have a positive urine mycotoxin test (or may have mycotoxins in the urine and not be ill as a result); thus the need for different "lenses" or types of tests.  In my experience, many different "lenses" have value and are very necessary. 

Enter myMycoLab as a "lens" that may be helpful in assessing the potential for mycotoxin-associated illness.  I did a podcast with Dr. Andrew Campbell on this topic in episode 114 and appreciate the work that he has done to help so many in his career.  

myMycoLab looks for IgG and IgE antibodies to mycotoxins and is an indirect test; much like looking for antibodies to an infection rather than looking for the antigen itself.  An immune response to mycotoxins suggests the immune system has "seen" or is currently seeing one or more of the 12 different mycotoxins tested for on the panel.

Note: Since I did the myMycoLab testing below, they have added 2 new mycotoxins; Fumonisin B1 and Zearalenone.  This makes the total 14 mycotoxins in the panel.  The price did not increase with these additions.

I have done the myMycoLab testing twice; once in 2020 and again in late 2023.  

In 2020, I had very high IgG mycotoxin antibodies and very low IgE mycotoxin antibodies.  In 2023, the IgG antibodies had reduced as compared to the 2020 test, but I now had some IgE antibodies that were not present previously.

myMycoLab Results in 2020:

myMycoLab Results in Late 2023:

I have learned the following from Dr. Andrew Campbell on what the myMycoLab results may tell us:

  • IgG antibodies may be from current exposure and/or colonization; thus the external environment may need to be explored, and there may be a place for antifungal therapy to address colonization
  • IgG antibodies to a toxin, like a mycotoxin, do not persist in the body like an IgG antibody to an infection often does; the immune system has a memory for pathogens, but not for toxins
  • While IgG antibodies on myMycoLab are believed to go down quickly after the issue is addressed, there are many factors that may impact the timeframe of the clearance of the IgG mycotoxin antibodies including: age, comorbidities, nutritional status, other allergens, stress levels, reactive oxygen species, how sedentary one is, and how much exercise one gets
  • IgE antibodies are believed to be from current exposure and indicators that mast cells may be triggered.  In speaking with Dr. Jill Crista, she indicated that some of her patients with significant colonization appeared to show IgE mycotoxin antibodies as well but that this was unlikely to be a common explanation for IgE antibodies on myMycoLab
  • IgE antibodies could be from a home, a workplace, a school but can also be from less frequented places such as a church, gym, library, car, or even your doctor's office
  • Food is not believed to impact the myMycoLab results
  • Natural antifungals have not been observed to lead to health recovery and people remain sick
  • There is no correlation between myMycoLab results and urine mycotoxin testing results

I'm glad that we have multiple "lenses" through which to look at the potential contribution of mycotoxins to our health. 

My plan is to continue to address fungal exposures and/or colonization and to continue to monitor the myMycoLab results over time; much like I have with RealTime Labs urine mycotoxin testing for the past several years.  While it may seem a lofty goal at times, at some point, I hope to have both an entirely negative myMycoLab result and a negative urine mycotoxin result.  Onward....

Dr. Campbell has also shared a number of webinars and other informative videos which are available to watch here.  Dr. Campbell also kindly shared his latest publication The Great Masquerader:  Mycotoxins.

To learn more, visit myMycoLab.  

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